I don't have one, but I've noticed that many of these 8-bit XT/ISA cards without the backplane are really easy to accidentally stick in backwards. If this is the case, you WOULD fry the EEPROM since the power pins (+5V, -5V, -12V, +12V, and +5V) on the "B" side of the MB socket and would mate with Address pins 2, 4, 6, 8, and Data 6 (where they correspond if rotated 180 degrees) on the "A" side of the card edge.
If this is the case, and assuming you're using the lo-tech card rather than the one from Glitchworks (I haven't done enough reading on that one though it may have a similar logic) address 6 and 8 pins would, if the board is reversed, be receiving +12v and -12v, respectively, going straight into the EEPROM. Address 2, 4 and Data 6 (+/-5v) aren't of consequence since all the logic here runs at up to 5v anyways, but +/-12v WILL fry the EEPROM.
You may be able to get it going again by replacing the EEPROM chip (the big 32-pin chip, probably a SST 39SF010A, they're about $2.50CDN from Digi-Key) and flashing with the relevant version of XT-IDE Universal BIOS using their utility.
Hope this helps. Good luck!