I am occasionally still getting stuff from GOG and playing it in Windows 2000, though ironically recent GOG releases include a DLL which makes everything fail to execute in WinXP. Under 2000 the extended kernel takes care of it but XP needs a different workaround. Many are re-releases, console ports, or translations. Plus a few from sources other than GOG.
Jade Empire, Two Worlds, Saints Row 2, Mount&Blade Warband, Torchlight 2, Cosmic Star Heroine, Trails in the Sky parts 1/2/3, Ys Seven, Ys Origins, Into the Breach, Hyperdimension Neptunia parts 1/2/3, Pillars of Eternity, Agarest: Generations of War, Freedom Planet, Oniken, Sins of a Solar Empire, Xanadu Next, Tempest of the Heavens and Earth, Shank 1/2