FedEx Ground will carry packages up to 150lb, but charge surcharges over 70lb. With that said, just because you can, that doesn't mean that you should.....
As Chuck says, LTL freight is a tried and tested method and you should go through a broker like a packing store or similar, not just for price but also to help you with freight class, liftgate requirements and a dozen other things that you don't want to spend time learning about.
Another option, if it's under 100lb is Greyhound Package Express. It's bus station to bus station, so you won't get tracking that's acceptable as proof of delivery for online intermediaries, but it's cheap and the packages are hand carried for transfer between vehicles, minimizing the risk of damage. I've used them a couple of times and have been happy with the results.